Cyclohexanone

Cyclohexanone

SCHEMBL2259986

CCOC(C)=O.O=C1CCCCC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.58
LMNA P02545 4/20 0.58
HSD17B10 Q99714 3/20 0.58
TRIM24 O15164 2/20 0.46
TRIM33 Q9UPN9 2/20 0.46
TSHR P16473 1/20 0.39
CYP2D6 P10635 1/20 0.37
ALOX15 P16050 3/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
GAA P10253 2/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
BRD4 O60885 1/20 0.35
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
SOAT1 P35610 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cycloheptanone SCHEMBL10412695 1.00 ALDH1A1 (0.58) ALDH1A1LMNAHSD17B10TRIM24TRIM33
Ethyl Acetate SCHEMBL7986575 0.98 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TRIM24TRIM33
Cyclohexanone SCHEMBL30818023 0.88 ALDH1A1 (0.45) ALDH1A1LMNAHSD17B10TRIM24TRIM33
Toluene SCHEMBL29256806 0.84 ALDH1A1 (0.45) ALDH1A1LMNAHSD17B10TSHRCYP2D6
Cyclohexane SCHEMBL509143 0.84 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL5908851 0.84 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL17156367 0.84 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL1172967 0.84 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL416739 0.84 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15
Cyclohexane SCHEMBL232777 0.84 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496177-B Method for preparing kali lazine and intermediate thereof 北京耀诚惠仁科技有限公司 2024-10-01 CN claimed
CN-117550989-B Preparation method of trans-2- (4-aminocyclohexyl) ethyl acetate hydrochloride 泰州精英化成医药科技有限公司 2024-09-27 CN claimed
CN-118496177-A Method for preparing kali lazine and intermediate thereof 北京耀诚惠仁科技有限公司 2024-08-16 CN claimed
CN-117550989-A Preparation method of trans-2- (4-aminocyclohexyl) ethyl acetate hydrochloride 泰州精英化成医药科技有限公司 2024-02-13 CN claimed
CN-113603803-B Method for simultaneously extracting phytosterol and polysaccharide from dragon fruit stems 广西壮族自治区农业科学院 2022-12-23 CN claimed
CN-113603803-A Method for simultaneously extracting phytosterol and polysaccharide from dragon fruit stems 广西壮族自治区农业科学院 2021-11-05 CN claimed
CN-104049046-A Method for detecting dimethyl fumarate in body lotion NANJING MAISIDE RESTAURANT MAN CO LTD 2014-09-17 CN claimed
US-4036842-A FRIEDEL CRAFTS CATALYST AMERICAN HOME PRODUCTS CORPORATION (US) 1977-07-19 US claimed
CN-119059963-A Benzobicyclo compound Process for the preparation of intermediates 广州市联瑞制药有限公司 2024-12-03 CN disclosed
CN-118974037-A Benzobicyclo compound and preparation method and application thereof 广州市联瑞制药有限公司 2024-11-15 CN disclosed
CN-118496177-B Method for preparing kali lazine and intermediate thereof 北京耀诚惠仁科技有限公司 2024-10-01 CN disclosed
CN-117550989-B Preparation method of trans-2- (4-aminocyclohexyl) ethyl acetate hydrochloride 泰州精英化成医药科技有限公司 2024-09-27 CN disclosed
WO-2024183807-A1 ARYL FUSED IMIDAZOLE COMPOUND AND MEDICAL USE THEREOF 哈尔滨三联药业股份有限公司 2024-09-12 WO disclosed
CN-118496177-A Method for preparing kali lazine and intermediate thereof 北京耀诚惠仁科技有限公司 2024-08-16 CN disclosed
US-4808608-A ANTIALLERGENS, HYPOTENSIVE AGENT, ANTICOAGULANT MERCK & CO., INC. (US) 1989-02-28 US disclosed
EP-0300676-A2 Tetrahydrocarbazole 1-alkanoic acids MERCK FROSST CANADA INC. (CA) 1989-01-25 EP disclosed
EP-0239306-A2 Tetrahydrocarbazole esters MERCK FROSST CANADA INC. (CA) 1987-09-30 EP disclosed
EP-0234708-A1 Tetrahydrocarbazole 1-alkanoic acids MERCK FROSST CANADA INC. (CA) 1987-09-02 EP disclosed
US-4021451-A P-(3,4-DIHYDRO-1-METHYL-1H-(1)BENZOTHIENO(2,3-C)PYRAN-1-YL)PHENYL) -ACETIC ACID AMERICAN HOME PRODUCTS CORPORATION (US) 1977-05-03 US disclosed
US-3983129-A INSECTICIDES ROUSSEL-UCLAF (FR) 1976-09-28 US disclosed