Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22600352 | 0.93 | THRB (0.43) | THRBRARBPOLBAPEX1HTT | |
| SCHEMBL20672253 | 0.92 | RARB (0.42) | THRBRARBPOLBAPEX1HTT | |
| SCHEMBL802826 | 0.92 | RARB (0.42) | THRBRARBPOLBAPEX1HTT | |
| SCHEMBL18511295 | 0.91 | THRB (0.49) | THRBRARBRARARARGS1PR1 | |
| SCHEMBL10024001 | 0.90 | RARB (0.40) | THRBRARBPOLBAPEX1HTT | |
| SCHEMBL13111492 | 0.90 | RARB (0.40) | THRBRARBPOLBAPEX1HTT | |
| SCHEMBL803177 | 0.90 | THRB (0.49) | THRBRARBRARARARGS1PR1 | |
| SCHEMBL12092908 | 0.89 | RARB (0.46) | THRBRARBPOLBAPEX1HTT | |
| SCHEMBL10040733 | 0.89 | THRB (0.46) | THRBRARBRARARARGS1PR1 | |
| SCHEMBL22600437 | 0.89 | THRB (0.58) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339884-A1 | LIQUID CRYSTAL COMPOSITION AND USE THEREOF | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2020-10-29 | — | — | US | disclosed |