Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503362 | 0.98 | MAPT (0.57) | MAPTRXFP1LTB4RTBXAS1HDAC6 | |
| SCHEMBL12017476 | 0.87 | FFAR1 (0.58) | MAPTFFAR1 | |
| SCHEMBL5353446 | 0.85 | MEN1 (0.63) | MAPTRXFP1TBXAS1HDAC6HDAC1 | |
| SCHEMBL22600357 | 0.84 | MAPT (0.55) | MAPTRXFP1LTB4RTBXAS1HDAC6 | |
| SCHEMBL5106598 | 0.84 | MEN1 (0.65) | MAPTRXFP1HDAC6HDAC1HDAC3 | |
| SCHEMBL1197247 | 0.84 | MAPT (0.78) | MAPTRXFP1LTB4RTBXAS1HDAC6 | |
| SCHEMBL17846038 | 0.82 | KMT2A (0.55) | MAPTSMN1; SMN2 | |
| SCHEMBL25059243 | 0.81 | NPC1 (0.47) | MAPTHDAC6HDAC1HDAC3MAPK1 | |
| SCHEMBL16450752 | 0.81 | MEN1 (0.56) | HDAC6HDAC1HDAC3HDAC4SMN1; SMN2 | |
| SCHEMBL765851 | 0.80 | MAPT (0.66) | MAPTRXFP1LTB4RTBXAS1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339596-A1 | FUROXAN-BASED COMPOUNDS AND USES THEREOF | UNIVERSITY OF MASSACHUSETTS | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339596-A1 | FUROXAN-BASED COMPOUNDS AND USES THEREOF | PARK7, HTT, PRDX5 | MAPT 104/4885RXFP1 2398/4885LTB4R 734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.