SCHEMBL22600702

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22600551	0.89	PARP1 (0.44)	TMIGD3ADORA1PARP1CDC7PIM1
	SCHEMBL24378773	0.85	PARP1 (0.44)	PARP1TNKSTNKS2IRAK4TLR9
	SCHEMBL25795251	0.85	CDC7 (0.38)	TMIGD3ADORA1CDC7PIM1CSNK2B
	SCHEMBL24378849	0.85	PARP1 (0.41)	TMIGD3ADORA1PARP1CDC7PIM1
	SCHEMBL22600708	0.84	CDC7 (0.37)	TMIGD3ADORA1CDC7PIM1CSNK2B
	SCHEMBL22600573	0.82	PARP14 (0.41)	TMIGD3ADORA1CDC7PIM1CSNK2B
	SCHEMBL22600706	0.78	ALDH1A1 (0.33)	TLR9TLR8TLR7
	SCHEMBL22600592	0.78	PARP14 (0.38)	TMIGD3ADORA1CDC7PIM1CSNK2B
	SCHEMBL22600737	0.77	PARP1 (0.41)	TMIGD3ADORA1PARP1CDC7PIM1
	SCHEMBL29222245	0.76	PARP1 (0.44)	TMIGD3ADORA1PARP1CDC7PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.