SCHEMBL22600767

SCHEMBL22600767

C/C=C\C(=C/CC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
CES2 O00748 3/20 0.35
CES1 P23141 3/20 0.35
CYP3A4 P08684 2/20 0.33
LMNA P02545 2/20 0.33
AKT1 P31749 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
PTGS2 P35354 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
HSD17B10 Q99714 1/20 0.32
RECQL P46063 1/20 0.32
ESR1 P03372 3/20 0.32
ESR2 Q92731 2/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7710925 0.85 CYP3A4 (0.38) ATMCES2CES1CYP3A4LMNA
SCHEMBL19871616 0.81 MAPT (0.39) MAPT
SCHEMBL22315200 0.81 AKT1 (0.35) ATMLMNAAKT1CHRNB2CHRNB4
SCHEMBL6838562 0.81 HTT (0.36) CYP3A4CYP1A2CYP2D6KMT2A
SCHEMBL6838561 0.81 HTT (0.36) CYP3A4CYP1A2CYP2D6KMT2A
SCHEMBL28085607 0.81 ATM (0.38) ATMCES2CES1CYP3A4LMNA
SCHEMBL18460837 0.81 ATM (0.38) ATMCES2CES1CYP3A4LMNA
SCHEMBL13012265 0.79 AKT1 (0.38) ATMCES2CES1LMNAAKT1
SCHEMBL30924817 0.79 ATM (0.37) ATMCES2CES1LMNAAKT1
SCHEMBL15826777 0.79 ACHE (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3053910-B1 ANILINE DERIVATIVES AND USES THEREOF NISSAN CHEMICAL CORP (JP) 2021-04-28 EP disclosed
US-20200343453-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING ELEMENT, AND COMPOUND Kyushu University, University Corporation (JP) 2020-10-29 US disclosed