Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22601140 | 0.90 | SLC16A3 (0.42) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL22587804 | 0.88 | KDM4E (0.44) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL24313791 | 0.85 | KDM4E (0.51) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL31723074 | 0.85 | KDM4E (0.51) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL22600971 | 0.83 | RAB9A (0.42) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL22587970 | 0.83 | KMT2A (0.43) | KMT2APTGER4PGR | |
| SCHEMBL22587719 | 0.83 | SLC16A3 (0.41) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL22588229 | 0.83 | RAB9A (0.47) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL22588241 | 0.82 | KDM4E (0.44) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL22588194 | 0.82 | PTGER4 (0.39) | KMT2AALDH1A1HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959202-B1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AG (DE) | 2023-08-16 | — | — | EP | claimed |
| EP-3959202-B1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AG (DE) | 2023-08-16 | — | — | EP | disclosed |
| WO-2020216701-A1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |