Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22601555 | 0.79 | MAP3K5 (0.36) | MAP3K5 | |
| SCHEMBL28848714 | 0.78 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL21461042 | 0.78 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL28653518 | 0.78 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL23510668 | 0.78 | MAP3K5 (0.45) | MAP3K5 | |
| SCHEMBL21461157 | 0.74 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL235293 | 0.74 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL21848985 | 0.74 | CYP2C9 (0.36) | — | |
| Hydrochloric Acid SCHEMBL28657089 | 0.73 | MAP3K5 (0.51) | MAP3K5 | |
| SCHEMBL28668610 | 0.73 | MAP3K5 (0.53) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339530-A1 | UREA DERIVATIVES AS INHIBITORS OF ASK1 | HEPAGENE THERAPEUTICS, INC. (VG) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339530-A1 | UREA DERIVATIVES AS INHIBITORS OF ASK1 | ATF1, ERN1, MAP3K1 | MAP3K5 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.