Benzoic Acid

Benzoic Acid

SCHEMBL226025

O=C(O)c1ccccc1.OCCO

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.78
DAO P14920 1/20 0.78
NAPRT Q6XQN6 1/20 0.78
CES1 P23141 4/20 0.64
CES2 O00748 3/20 0.64
SRD5A2 P31213 2/20 0.64
TP53 P04637 1/20 0.58
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 2/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TRPA1 O75762 2/20 0.50
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL2779805 1.00 TSHR (0.78) TSHRDAONAPRTCES1CES2
Benzoic Acid SCHEMBL27410268 1.00 TSHR (0.78) TSHRDAONAPRTCES1CES2
Benzoic Acid SCHEMBL27835214 1.00 TSHR (0.78) TSHRDAONAPRTCES1CES2
Benzoic Acid SCHEMBL1254290 1.00 TSHR (0.78) TSHRDAONAPRTCES1CES2
Benzoic Acid SCHEMBL606680 1.00 TSHR (0.78) TSHRDAONAPRTCES1CES2
Benzoic Acid SCHEMBL9347407 1.00 TSHR (0.78) TSHRDAONAPRTCES1CES2
Benzoic Acid SCHEMBL207614 1.00 TSHR (0.78) TSHRDAONAPRTCES1CES2
Benzoic Acid SCHEMBL10338171 0.97 TSHR (0.74) TSHRDAONAPRTCES1CES2
Terephthalic Acid SCHEMBL4963476 0.97 TSHR (0.74) TSHRDAONAPRTCES1CES2
Benzoic Acid SCHEMBL3958335 0.93 TSHR (0.67) TSHRDAONAPRTCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111430648-B Polyimide lithium ion battery diaphragm, preparation method and lithium ion battery 深圳市华之美科技有限公司 2023-05-12 CN claimed
US-11629240-B2 Formulation of di(4-tert-butylcyclohexyl) peroxydicarbonate NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-04-18 US claimed
EP-3728187-B1 PROCESS FOR PREPARING A POWDERY ORGANIC PEROXIDE FORMULATION NOURYON CHEMICALS INT BV (NL) 2022-06-22 EP claimed
CN-113122890-B Cyanide-free alkaline gold plating solution and electroplating method thereof 深圳市缤纷珠宝开发有限公司 2022-06-10 CN claimed
CN-114230981-A Pumpable and thermally expandable filler composition SIKA技术股份公司 2022-03-25 CN claimed
US-20210009786-A1 FORMULATION OF DI(4-TERT-BUTYLCYCLOHEXYL) PEROXYDICARBONATE NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2021-01-14 US claimed
EP-3728187-A1 PROCESS FOR PREPARING A POWDERY ORGANIC PEROXIDE FORMULATION Nouryon Chemicals International B.V. (NL) 2020-10-28 EP claimed
US-20200331854-A1 PROCESS FOR PREPARING A POWDERY ORGANIC PEROXIDE FORMULATION NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2020-10-22 US claimed
CN-111770913-A Process for preparing pulverulent organic peroxide formulations 诺力昂化学品国际有限公司 2020-10-13 CN claimed
CN-111430648-A Polyimide lithium ion battery diaphragm, preparation method and lithium ion battery 胡欣宇 2020-07-17 CN claimed
WO-2001096412-A1 A CATALYST FOR ETHYLENE HOMO- AND COPOLYMERIZATION SAMSUNG GENERAL CHEMICALS CO. LTD. (KR) 2001-12-20 WO claimed
WO-2001092345-A1 A METHOD FOR PRODUCING ETHYLENE HOMO- AND CO-POLYMER SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-12-06 WO claimed
WO-2001081432-A1 CATALYST FOR PRODUCING AN ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE AND METHOD FOR PRODUCING AN ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE USING THE SAME SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-11-01 WO claimed
US-20010031694-A1 Catalyst for polymerization and co-polymerization of ethylene SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-10-18 US claimed
US-6291385-B1 Catalyst for polymerization or copolymerization of olefin SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-09-18 US claimed
WO-2001040320-A1 CATALYST FOR POLYMERIZATION AND CO-POLYMERIZATION OF ETHYLENE SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-06-07 WO claimed
WO-2000073355-A1 A CATALYST FOR ETHYLENE HOMO- AND CO-POLYMERIZATION SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2000-12-07 WO claimed
WO-1997030115-A1 ANTI-BACTERIAL FILM SUITABLE FOR FOOD PACKAGING HITACHI-BORDEN CHEMICAL PRODUCTS, INC. (JP) 1997-08-21 WO claimed
US-5459116-A Magnesium, titanium, halogen and hydroxyalkyl ester compounds; stereospecific, bulk density; polyethylene SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 1995-10-17 US claimed
US-4656214-A DIESTERS EXXON RESEARCH & ENGINEERING CO. (US) 1987-04-07 US claimed