Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | DAO | P14920 | 1/20 | 0.74 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.68 |
| ▸ | CES1 | P23141 | 3/20 | 0.68 |
| ▸ | CES2 | O00748 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL207614 | 0.97 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL226025 | 0.97 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL606680 | 0.97 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL1254290 | 0.97 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL2779805 | 0.97 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL9347407 | 0.97 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL27410268 | 0.97 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL27835214 | 0.97 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL10338171 | 0.95 | TSHR (0.74) | TSHRDAONAPRTSRD5A2CES1 | |
| Ethylene Glycol SCHEMBL11239436 | 0.93 | SRD5A2 (0.82) | TSHRDAONAPRTSRD5A2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379631-B1 | FOR MEDICAL EQUIPMENT; POLYESTERS SUCH AS POLYBENZOATE NAPHTHALATE, POLYBENZOATE TEREPHTHALATE BISPHENOL ISOPHTHALATE; HIGH STRENGTH | JOHNSON & JOHNSON MEDICAL, INC. | 2002-04-30 | — | — | US | claimed |
| EP-0815876-A2 | Instrument sterilization container formed of a liquid crystal polymer | JOHNSON & JOHNSON MEDICAL, INC. (US) | 1998-01-07 | — | — | EP | claimed |
| WO-2015107095-A1 | POLYMER FILM | CEDAR ADVANCED TECHNOLOGY GROUP LTD. (CH) | 2015-07-23 | — | — | WO | disclosed |
| EP-1545303-A4 | IMPLANTABLE WIRELESS SENSOR FOR BLOOD PRESSURE MEASUREMENT WITHIN AN ARTERY | CARDIOMEMS INC (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7147604-B1 | High Q factor sensor | CARDIOMEMS, INC. (US) | 2006-12-12 | — | — | US | disclosed |
| EP-1545303-A2 | IMPLANTABLE WIRELESS SENSOR FOR BLOOD PRESSURE MEASUREMENT WITHIN AN ARTERY | CARDIOMEMS, INC. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014456-A9 | IMPLANTABLE WIRELESS SENSOR FOR BLOOD PRESSURE MEASUREMENT WITHIN AN ARTERY | CARDIOMEMS INC (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004014456-A2 | IMPLANTABLE WIRELESS SENSOR FOR BLOOD PRESSURE MEASUREMENT WITHIN AN ARTERY | CARDIOMEMS, INC. (US) | 2004-02-19 | — | — | WO | disclosed |
| US-6692693-B2 | A STERILIZATION CONTAINER FOR STERILIZING, STORING AND TRANSPORTING MEDICAL INSTRUMENTS IS FORMED OF A LIQUID CRYSTAL POLYMER, SUCH AS AN AROMATIC POLYESTER | ETHICON, INC. | 2004-02-17 | — | — | US | disclosed |
| US-6692693-B2 | A STERILIZATION CONTAINER FOR STERILIZING, STORING AND TRANSPORTING MEDICAL INSTRUMENTS IS FORMED OF A LIQUID CRYSTAL POLYMER, SUCH AS AN AROMATIC POLYESTER | ETHICON, INC. | 2004-02-17 | — | — | US | disclosed |
| CN-1135118-C | Container of LCD polymer for apparatus sterilizing | �Ϳ���ҽҩ��˾ | 2004-01-21 | — | — | CN | disclosed |
| US-20020192108-A1 | Instrument sterilization container formed of a liquid crystal polymer | ETHICON, INC. | 2002-12-19 | — | — | US | disclosed |
| US-20020192108-A1 | Instrument sterilization container formed of a liquid crystal polymer | ETHICON, INC. | 2002-12-19 | — | — | US | disclosed |
| US-6379631-B1 | FOR MEDICAL EQUIPMENT; POLYESTERS SUCH AS POLYBENZOATE NAPHTHALATE, POLYBENZOATE TEREPHTHALATE BISPHENOL ISOPHTHALATE; HIGH STRENGTH | JOHNSON & JOHNSON MEDICAL, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6379631-B1 | FOR MEDICAL EQUIPMENT; POLYESTERS SUCH AS POLYBENZOATE NAPHTHALATE, POLYBENZOATE TEREPHTHALATE BISPHENOL ISOPHTHALATE; HIGH STRENGTH | JOHNSON & JOHNSON MEDICAL, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6193932-B1 | Sterilization container and instrument holder therefor | ETHICON, INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0815876-A3 | Instrument sterilization container formed of a liquid crystal polymer | JOHNSON & JOHNSON MEDICAL, INC. (US) | 1999-12-15 | — | — | EP | disclosed |
| CN-1182624-A | Container of LCD polymer for apparatus sterilizing | JOHNSON & JOHNSON MEDICAL (US) | 1998-05-27 | — | — | CN | disclosed |
| EP-0815876-A2 | Instrument sterilization container formed of a liquid crystal polymer | JOHNSON & JOHNSON MEDICAL, INC. (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0815876-A2 | Instrument sterilization container formed of a liquid crystal polymer | JOHNSON & JOHNSON MEDICAL, INC. (US) | 1998-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020192108-A1 | Instrument sterilization container formed of a liquid crystal polymer | NASP, ALKBH3, TST | TSHR 3710/4885DAO 1032/4885NAPRT 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.