Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | TPO | P07202 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22603986 | 0.87 | AHR (0.42) | MPOTPOBRD4 | |
| SCHEMBL15672062 | 0.81 | BRD4 (0.39) | MPOTPOHTR1ABRD4 | |
| SCHEMBL23023182 | 0.78 | HTR2A (0.46) | MPOTPOBRD4 | |
| SCHEMBL13498251 | 0.77 | HTT (0.44) | HTTKMT2ALMNAPABPC1GLA | |
| SCHEMBL10433983 | 0.75 | KMT2A (0.57) | HTTKMT2ALMNAPABPC1GLA | |
| Hydrochloric Acid SCHEMBL10433976 | 0.74 | KMT2A (0.56) | HTTKMT2ALMNAPABPC1GLA | |
| SCHEMBL15492796 | 0.73 | HTT (0.55) | HTTKMT2ALMNAPABPC1GLA | |
| SCHEMBL1253321 | 0.73 | HTR2A (0.47) | BRD4 | |
| SCHEMBL9227710 | 0.71 | KMT2A (0.52) | HTTKMT2ALMNAPABPC1GLA | |
| SCHEMBL11478614 | 0.70 | HTR2A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339502-A1 | COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS | UNIVERSITÄT ZU KÖLN (DE) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339502-A1 | COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS | ALPG, RARB, RARG | HTT 2654/4885KMT2A 2948/4885LMNA 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.