Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | TPO | P07202 | 2/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 5/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22603988 | 0.87 | HTT (0.49) | MPOTPOBRD4 | |
| SCHEMBL15672062 | 0.77 | BRD4 (0.39) | AHRHTR2AHTR2CMPOTPO | |
| SCHEMBL23023182 | 0.76 | HTR2A (0.46) | AHRHTR2AHTR2CMPOTPO | |
| SCHEMBL15805488 | 0.74 | ACHE (0.46) | SSTR3 | |
| SCHEMBL1253321 | 0.74 | HTR2A (0.47) | AHRHTR2AHTR2CBRD4ADORA2A | |
| SCHEMBL15672063 | 0.72 | AHR (0.41) | AHRHTR2AHTR2CBRD4DRD4 | |
| SCHEMBL11478614 | 0.71 | HTR2A (0.51) | AHRHTR2AHTR2CADORA2AADORA1 | |
| SCHEMBL13284394 | 0.70 | DRD4 (0.50) | AHRMPOTPODRD4JAK2 | |
| SCHEMBL8313742 | 0.69 | GLA (0.50) | — | |
| SCHEMBL1395817 | 0.69 | HTR2A (0.52) | AHRHTR2AHTR2CADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339502-A1 | COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS | UNIVERSITÄT ZU KÖLN (DE) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339502-A1 | COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS | ALPG, RARB, RARG | AHR 2431/4885HTR2A 4300/4885HTR2C 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.