Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | NCF1 | P14598 | 6/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24307440 | 1.00 | HRH3 (0.35) | HRH3NCF1LTA4HAPP | |
| SCHEMBL22604304 | 0.91 | NCF1 (0.38) | NCF1 | |
| SCHEMBL22604308 | 0.91 | NCF1 (0.38) | NCF1 | |
| SCHEMBL22604312 | 0.86 | NCF1 (0.41) | HRH3NCF1LTA4HAPP | |
| SCHEMBL24307476 | 0.74 | — | — | |
| SCHEMBL21920504 | 0.72 | NPC1 (0.51) | LTA4H | |
| SCHEMBL9446753 | 0.72 | NCF1 (0.43) | NCF1 | |
| SCHEMBL1063334 | 0.71 | CACNA1I (0.42) | — | |
| SCHEMBL12392104 | 0.71 | CACNA1I (0.42) | — | |
| SCHEMBL30320162 | 0.71 | CACNA1I (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216071-A1 | DIMERIC OR POLYMERIC FORM OF MUTANT IDH INHIBITOR | 上海仕谱生物科技有限公司 | 2020-10-29 | — | — | WO | disclosed |