Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605173 | 0.90 | MEN1 (0.43) | MEN1KMT2AADRB2ADRB1SIGMAR1 | |
| SCHEMBL27098253 | 0.88 | TSHR (0.42) | ADRB2ADRB1SIGMAR1CYP2D6CYP1A2 | |
| SCHEMBL22452370 | 0.83 | ADRB2 (0.38) | ADRB2ADRB1SIGMAR1CYP2D6CYP1A2 | |
| SCHEMBL22452289 | 0.83 | ADRB2 (0.38) | ADRB2ADRB1SIGMAR1CYP2D6CYP1A2 | |
| SCHEMBL22452408 | 0.79 | NR2E1 (0.50) | MEN1KMT2AADRB2ADRB1SIGMAR1 | |
| SCHEMBL22452287 | 0.79 | NR2E1 (0.50) | MEN1KMT2AADRB2ADRB1SIGMAR1 | |
| SCHEMBL27098252 | 0.77 | TSHR (0.45) | MEN1KMT2AADRB2ADRB1SIGMAR1 | |
| SCHEMBL22452285 | 0.74 | MEN1 (0.53) | MEN1KMT2AADRB2ADRB1SIGMAR1 | |
| SCHEMBL22604990 | 0.72 | NR2E1 (0.49) | MEN1KMT2AADRB2ADRB1SIGMAR1 | |
| SCHEMBL30668208 | 0.70 | EPHX1 (0.49) | MEN1KMT2AOPRM1OPRK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200340982-A1 | PHOTOAFFINITY PROBES | PROMEGA CORPORATION | 2020-10-29 | — | — | US | disclosed |