Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | MLNR | O43193 | 3/20 | 0.58 |
| ▸ | ME2 | P23368 | 1/20 | 0.55 |
| ▸ | ME1 | P48163 | 1/20 | 0.55 |
| ▸ | ME3 | Q16798 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.52 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605564 | 0.85 | EPHX2 (0.56) | HRH3MLNRME2ME1ME3 | |
| SCHEMBL16002963 | 0.85 | MEN1 (0.69) | MLNREPHX2CNR1TEAD1SIGMAR1 | |
| SCHEMBL22605639 | 0.85 | HRH3 (0.62) | HRH3MLNRME2ME1ME3 | |
| SCHEMBL16002877 | 0.83 | ALDH1A1 (0.52) | MLNRME2ME1ME3EPHX2 | |
| SCHEMBL22588108 | 0.82 | HRH3 (0.59) | HRH3MLNRME2ME1ME3 | |
| SCHEMBL16003039 | 0.82 | GFER (0.53) | ME2ME1ME3EPHX2SIGMAR1 | |
| SCHEMBL16002993 | 0.80 | MAPT (0.60) | HRH3 | |
| SCHEMBL22605589 | 0.80 | MLNR (0.54) | HRH3MLNRME2ME1ME3 | |
| SCHEMBL22605590 | 0.80 | EPHX2 (0.50) | HRH3MLNRME2ME1ME3 | |
| SCHEMBL22588179 | 0.80 | MLNR (0.54) | HRH3MLNRME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |