SCHEMBL22606013

SCHEMBL22606013

CCOC(=O)CC(C)[C@@](C)(CC)CCl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
ALDH1A1 P00352 7/20 0.35
TRPA1 O75762 1/20 0.35
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 2/20 0.34
TSHR P16473 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 2/20 0.33
CHRM1 P11229 1/20 0.33
ADORA1 P30542 1/20 0.33
MMP8 P22894 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP4F2 P78329 2/20 0.31
CYP4A11 Q02928 2/20 0.31
CYP2D6 P10635 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16254841 0.78 GAA (0.43) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL13602465 0.77 GAA (0.46) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL17266817 0.74 GAA (0.43) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21052497 0.73 GAA (0.41) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1904864 0.72 GAA (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL197988 0.72 GAA (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1237869 0.72 GAA (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11247658 0.71 GAA (0.40) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7186530 0.71 GAA (0.43) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL9132435 0.70 MGAM (0.46) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020215357-A1 METHOD FOR PREPARING CHIRAL β-HYDROXYCARBOXYLATE COMPOUND 呼延旺 2020-10-29 WO disclosed