Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22675389 | 1.00 | CXCR2 (0.35) | CXCR2 | |
| SCHEMBL22675698 | 0.79 | CXCR2 (0.34) | CXCR2 | |
| SCHEMBL22675390 | 0.75 | CXCR2 (0.38) | CXCR2 | |
| SCHEMBL22606139 | 0.75 | CXCR2 (0.38) | CXCR2 | |
| SCHEMBL19656903 | 0.69 | UGT2B17 (0.30) | — | |
| SCHEMBL8195756 | 0.68 | KDM4E (0.42) | — | |
| SCHEMBL22675392 | 0.67 | CXCR2 (0.35) | CXCR2 | |
| SCHEMBL22606412 | 0.67 | CXCR2 (0.35) | CXCR2 | |
| SCHEMBL10160746 | 0.64 | TSHR (0.33) | — | |
| SCHEMBL22606410 | 0.61 | HRH2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136315-B2 | CXCR2 antagonist | MEDSHINE DISCOVERY INC. (CN) | 2021-10-05 | — | — | US | disclosed |
| US-20200339549-A1 | CXCR2 ANTAGONIST | Shenzhen Optimum Biological Technology Co., Ltd (CN) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136315-B2 | CXCR2 antagonist | CXCR2, CXCR3, CXCR1 | CXCR2 1/4885 |
| US-20200339549-A1 | CXCR2 ANTAGONIST | CXCR2, CXCR3, CXCR1 | CXCR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.