Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 7/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17662299 | 0.83 | KDM4E (0.45) | KDM4EL3MBTL1NAAACNR1CNR2 | |
| SCHEMBL4787017 | 0.81 | TSHR (0.48) | KDM4ENAAAPIK3CDTSHRMAPK1 | |
| SCHEMBL9310220 | 0.79 | KDM4E (0.38) | KDM4ENAAACNR1CNR2ALDH1A1 | |
| SCHEMBL20329218 | 0.77 | KDM4E (0.41) | KDM4ENAAACNR1CNR2ALDH1A1 | |
| SCHEMBL9310675 | 0.77 | KMT2A (0.45) | KDM4ENAAACNR1CNR2ALDH1A1 | |
| SCHEMBL20105 | 0.76 | — | — | |
| SCHEMBL510011 | 0.76 | — | — | |
| SCHEMBL6378864 | 0.76 | ALDH1A1 (0.44) | KDM4EL3MBTL1NAAAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL18050151 | 0.75 | KDM4E (0.47) | KDM4ENAAACNR1CNR2ALDH1A1 | |
| SCHEMBL1712876 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |