Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22607637 | 0.91 | MAPT (0.32) | RAD52CCNA2CDK2CCNA1MAPT | |
| SCHEMBL22607652 | 0.91 | ROCK2 (0.32) | RAD52ROCK2CCNA2CDK2CCNA1 | |
| SCHEMBL22607642 | 0.90 | CCNA2 (0.31) | RAD52CCNA2CDK2CCNA1 | |
| SCHEMBL22607669 | 0.90 | BRD4 (0.34) | — | |
| SCHEMBL22607667 | 0.88 | CCNA2 (0.30) | RAD52CCNA2CDK2CCNA1MAPT | |
| SCHEMBL22607655 | 0.88 | CCNA2 (0.32) | RAD52CCNA2CDK2CCNA1 | |
| SCHEMBL22607641 | 0.87 | KDM1A (0.32) | RAD52CCNA2CDK2CCNA1MAPT | |
| SCHEMBL16334004 | 0.87 | CNR2 (0.33) | RAD52KMT2ACCNA2CDK2CCNA1 | |
| SCHEMBL22607659 | 0.87 | ROCK2 (0.32) | RAD52ROCK2CCNA2CDK2CCNA1 | |
| SCHEMBL22607647 | 0.86 | USP30 (0.33) | RAD52ROCK2CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |