Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22607660 | 0.90 | CCNA2 (0.30) | — | |
| SCHEMBL22607632 | 0.90 | EHMT2 (0.30) | ABCB1EHMT2EHMT1 | |
| SCHEMBL17783221 | 0.89 | CCNA2 (0.30) | — | |
| SCHEMBL16377785 | 0.86 | EHMT2 (0.31) | EHMT2EHMT1 | |
| SCHEMBL17783246 | 0.86 | KMT2A (0.32) | — | |
| SCHEMBL22607652 | 0.86 | ROCK2 (0.32) | ABCB1 | |
| SCHEMBL16334004 | 0.85 | CNR2 (0.33) | — | |
| SCHEMBL22607635 | 0.85 | KMT2A (0.32) | — | |
| SCHEMBL22607647 | 0.85 | USP30 (0.33) | HTR2A | |
| SCHEMBL22607667 | 0.85 | CCNA2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |