Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP10 | Q9Y6W6 | 12/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31161895 | 1.00 | DUSP10 (0.67) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL24339461 | 0.90 | DUSP10 (0.62) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL24339746 | 0.90 | DUSP10 (0.62) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL24339475 | 0.88 | DUSP10 (0.59) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL24339474 | 0.86 | DUSP10 (0.64) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL30419466 | 0.80 | DUSP10 (1.00) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL22608851 | 0.80 | DUSP10 (1.00) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL25630450 | 0.77 | DUSP10 (0.69) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL22608821 | 0.73 | DUSP10 (0.71) | DUSP10KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL31161845 | 0.73 | DUSP10 (0.71) | DUSP10KDM4EMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240335445-A1 | Compounds and Compositions for Treating Fibrosis | UNIV YALE (US) | 2024-10-10 | — | — | US | claimed |
| EP-3732179-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING FIBROSIS | UNIV YALE (US) | 2024-05-01 | — | — | EP | claimed |
| CN-116687934-A | Compounds and compositions for treating fibrosis | 耶鲁大学 | 2023-09-05 | — | — | CN | claimed |
| CN-111670188-B | Compounds and compositions for treating fibrosis | 耶鲁大学 | 2023-06-23 | — | — | CN | claimed |
| US-20230181588-A1 | Compounds and Compositions for Treating Fibrosis | UNIV YALE (US) | 2023-06-15 | — | — | US | claimed |
| US-11504373-B2 | Compounds and compositions for treating fibrosis | YALE UNIVERSITY (US) | 2022-11-22 | — | — | US | claimed |
| US-20200390770-A1 | Compounds and Compositions for Treating Fibrosis | UNIV YALE (US) | 2020-12-17 | — | — | US | claimed |
| EP-3732179-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING FIBROSIS | Yale University (US) | 2020-11-04 | — | — | EP | claimed |
| CN-111670188-A | Compounds and compositions for the treatment of fibrosis | 耶鲁大学 | 2020-09-15 | — | — | CN | claimed |
| US-20240335445-A1 | Compounds and Compositions for Treating Fibrosis | UNIV YALE (US) | 2024-10-10 | — | — | US | disclosed |
| EP-3732179-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING FIBROSIS | UNIV YALE (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-116687934-A | Compounds and compositions for treating fibrosis | 耶鲁大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-111670188-B | Compounds and compositions for treating fibrosis | 耶鲁大学 | 2023-06-23 | — | — | CN | disclosed |
| US-20230181588-A1 | Compounds and Compositions for Treating Fibrosis | UNIV YALE (US) | 2023-06-15 | — | — | US | disclosed |
| US-11504373-B2 | Compounds and compositions for treating fibrosis | YALE UNIVERSITY (US) | 2022-11-22 | — | — | US | disclosed |
| US-11504373-B2 | Compounds and compositions for treating fibrosis | YALE UNIVERSITY (US) | 2022-11-22 | — | — | US | disclosed |
| US-20200390770-A1 | Compounds and Compositions for Treating Fibrosis | UNIV YALE (US) | 2020-12-17 | — | — | US | disclosed |
| US-20200390770-A1 | Compounds and Compositions for Treating Fibrosis | UNIV YALE (US) | 2020-12-17 | — | — | US | disclosed |
| EP-3732179-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING FIBROSIS | Yale University (US) | 2020-11-04 | — | — | EP | disclosed |
| CN-111670188-A | Compounds and compositions for the treatment of fibrosis | 耶鲁大学 | 2020-09-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335445-A1 | Compounds and Compositions for Treating Fibrosis | DUSP5, DUSP15, DUSP26 | DUSP10 6/4885KDM4E 349/4885MAPT 3232/4885 |
| US-11504373-B2 | Compounds and compositions for treating fibrosis | DUSP5, DUSP15, LPCAT3 | DUSP10 6/4885KDM4E 631/4885MAPT 3649/4885 |
| US-20230181588-A1 | Compounds and Compositions for Treating Fibrosis | DUSP5, DUSP15, DUSP26 | DUSP10 6/4885KDM4E 349/4885MAPT 3232/4885 |
| US-20200390770-A1 | Compounds and Compositions for Treating Fibrosis | DUSP5, DUSP15, LPCAT3 | DUSP10 6/4885KDM4E 631/4885MAPT 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.