Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 5/20 | 0.68 |
| ▸ | KAT2A | Q92830 | 4/20 | 0.68 |
| ▸ | EP300 | Q09472 | 3/20 | 0.68 |
| ▸ | MPI | P34949 | 11/20 | 0.46 |
| ▸ | G6PD | P11413 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903519 | 0.88 | KAT2B (0.51) | KAT2BKAT2AEP300MPIG6PD | |
| SCHEMBL1897468 | 0.82 | KAT2B (1.00) | KAT2BKAT2AEP300MPIG6PD | |
| SCHEMBL1905901 | 0.79 | KAT2B (0.56) | KAT2BKAT2AEP300MPIG6PD | |
| SCHEMBL12297905 | 0.72 | KAT2B (1.00) | KAT2BKAT2AEP300MPIG6PD | |
| SCHEMBL1904049 | 0.66 | KAT2B (0.55) | KAT2BKAT2AEP300MPIG6PD | |
| SCHEMBL1906226 | 0.66 | MPI (0.55) | KAT2BKAT2AEP300MPIG6PD | |
| SCHEMBL8371734 | 0.66 | MPI (0.74) | KAT2BMPIG6PDKDM4EALDH1A1 | |
| SCHEMBL1896492 | 0.66 | KAT2B (0.65) | KAT2BKAT2AEP300MPIG6PD | |
| SCHEMBL1908012 | 0.63 | KAT2B (0.54) | KAT2BKAT2AEP300MPIG6PD | |
| SCHEMBL21687131 | 0.62 | KAT2B (1.00) | KAT2BKAT2AEP300MPIG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3732180-A1 | COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS | Emory University (US) | 2020-11-04 | — | — | EP | claimed |
| EP-4319764-A2 | THIONUCLEOSIDES AS ANTIVIRAL AGENTS | Emory University (US) | 2024-02-14 | — | — | EP | disclosed |
| EP-4319762-A2 | NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS | Emory University (US) | 2024-02-14 | — | — | EP | disclosed |
| EP-4319763-A2 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | Emory University (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022217155-A2 | THIONUCLEOSIDES AS ANTIVIRAL AGENTS | EMORY UNIVERSITY (US) | 2022-10-13 | — | — | WO | disclosed |
| WO-2020247665-A1 | PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS | EMORY UNIVERSITY (US) | 2020-12-10 | — | — | WO | disclosed |
| EP-3732180-A1 | COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS | Emory University (US) | 2020-11-04 | — | — | EP | disclosed |