SCHEMBL226093

SCHEMBL226093

Clc1cc(Cl)cc(SSc2cc(Cl)cc(Cl)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
CYP3A4 P08684 3/20 0.42
TP53 P04637 1/20 0.42
ALDH1A1 P00352 3/20 0.37
SOD1 P00441 1/20 0.37
TPMT P51580 1/20 0.35
HSD17B10 Q99714 3/20 0.33
RECQL P46063 2/20 0.33
FBP1 P09467 2/20 0.32
IDO1 P14902 2/20 0.32
AHR P35869 1/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19885313 0.84 TSHR (0.40) TSHRCYP3A4TP53SOD1IDO1
SCHEMBL1646982 0.84 TSHR (0.40) TSHRCYP3A4TP53ALDH1A1SOD1
SCHEMBL6822918 0.80 TSHR (0.35) TSHR
SCHEMBL1962185 0.79 TSHR (0.57) TSHRCYP3A4TP53ALDH1A1SOD1
SCHEMBL4123128 0.76 TSHR (0.53) TSHRCYP3A4TP53ALDH1A1SOD1
SCHEMBL1646155 0.76 TSHR (0.38) TSHRCYP3A4TP53SOD1FBP1
1,3,5-Trichlorobenzene SCHEMBL429512 0.76
SCHEMBL18793369 0.73 TSHR (0.50) TSHRCYP3A4TP53ALDH1A1SOD1
SCHEMBL11042643 0.73 TSHR (0.50) TSHRCYP3A4TP53ALDH1A1SOD1
SCHEMBL6768913 0.73 TSHR (0.50) TSHRCYP3A4TP53ALDH1A1SOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1013 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115957617-A Dealkalized refining agent and preparation method and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-6444853-B1 FROM AROMATIC THIOETHER NIPPON FINECHEMICAL CO., LTD. (JP) 2002-09-03 US claimed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US claimed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US claimed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-20250018250-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-01-16 US disclosed
US-20240299812-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-09-12 US disclosed
US-20240269520-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-08-15 US disclosed
WO-2024160834-A1 METHOD FOR PRODUCING A POLYMER, IN PARTICULAR FOR A MEMBRANE, POLYMER, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-08-08 WO disclosed
EP-0449726-A1 Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient Mitsubishi Chemical Corporation (JP) 1991-10-02 EP disclosed
EP-0420763-A2 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof Mitsubishi Chemical Corporation (JP) 1991-04-03 EP disclosed
US-4983720-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-01-08 US disclosed
EP-0402481-A1 PRODUCTION OF POLYARYLENE THIOETHER RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1990-12-19 EP disclosed
US-4931542-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) 1990-06-05 US disclosed
EP-0281036-A2 A process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 TSHR 3570/4885CYP3A4 4002/4885TP53 2562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.