SCHEMBL1646155

SCHEMBL1646155

CCSSc1cc(Cl)cc(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
SOD1 P00441 1/20 0.33
FBP1 P09467 1/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1647142 0.80 FBP1 (0.45) TSHRFBP1
SCHEMBL1646292 0.76 LMNA (0.38) TSHRFBP1
SCHEMBL226093 0.76 TSHR (0.57) TSHRSOD1FBP1TP53CYP3A4
SCHEMBL1043789 0.75 SOD1 (0.44) TSHRSOD1TP53CYP3A4
SCHEMBL1648006 0.74 ALDH1A1 (0.36) TSHRFBP1TP53CYP3A4
SCHEMBL775573 0.71 FBP1 (0.32) FBP1
SCHEMBL1645351 0.71 FBP1 (0.32) FBP1
SCHEMBL3786477 0.70 SOD1 (0.39) TSHRSOD1
1,3,5-Trichlorobenzene SCHEMBL5940813 0.69 TSHR (0.67) TSHRTP53CYP3A4
SCHEMBL19885313 0.68 TSHR (0.40) TSHRSOD1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed