Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21069493 | 1.00 | CACNA1H (0.38) | CACNA1HHCRTR2DRD2MEN1KMT2A | |
| SCHEMBL21071400 | 1.00 | CACNA1H (0.38) | CACNA1HHCRTR2DRD2MEN1KMT2A | |
| SCHEMBL31587115 | 0.82 | CACNA1H (0.43) | CACNA1HHCRTR2DRD2MEN1KMT2A | |
| SCHEMBL28515788 | 0.81 | KDM4E (0.36) | CACNA1HALDH1A1TSHRBCHEMAOB | |
| SCHEMBL12021262 | 0.80 | ACKR3 (0.44) | CACNA1HHCRTR2DRD2MEN1KMT2A | |
| SCHEMBL13492044 | 0.80 | ACKR3 (0.44) | CACNA1HHCRTR2DRD2MEN1KMT2A | |
| SCHEMBL16020333 | 0.80 | ACKR3 (0.44) | CACNA1HHCRTR2DRD2MEN1KMT2A | |
| SCHEMBL8807179 | 0.79 | CACNA1H (0.41) | CACNA1HHCRTR2DRD2 | |
| SCHEMBL19558649 | 0.79 | HCRTR2 (0.41) | CACNA1HHCRTR2DRD2MEN1KMT2A | |
| SCHEMBL21166048 | 0.79 | HCRTR2 (0.41) | CACNA1HHCRTR2DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |