Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21069493 | 0.81 | CACNA1H (0.38) | CACNA1HBCHEALDH1A1MAOBTSHR | |
| SCHEMBL21071400 | 0.81 | CACNA1H (0.38) | CACNA1HBCHEALDH1A1MAOBTSHR | |
| SCHEMBL22609446 | 0.81 | CACNA1H (0.38) | CACNA1HBCHEALDH1A1MAOBTSHR | |
| SCHEMBL21069557 | 0.77 | PDK1 (0.45) | DRD4 | |
| SCHEMBL26925497 | 0.75 | BCHE (0.41) | BCHEMAOB | |
| SCHEMBL26923812 | 0.75 | BCHE (0.41) | BCHEMAOB | |
| SCHEMBL21813316 | 0.74 | ACKR3 (0.51) | KDM4ECACNA1HALDH1A1TDP1PKM | |
| SCHEMBL2769124 | 0.74 | DRD4 (0.61) | KDM4ECCR3ALDH1A1TDP1DRD4 | |
| SCHEMBL5429645 | 0.74 | DRD4 (0.61) | KDM4ECCR3ALDH1A1TDP1DRD4 | |
| SCHEMBL2770194 | 0.74 | DRD4 (0.61) | KDM4ECCR3ALDH1A1TDP1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |