Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071152 | 1.00 | DDB1 (0.55) | DDB1CRBNEGFR | |
| SCHEMBL21106382 | 0.90 | DDB1 (0.69) | DDB1CRBN | |
| SCHEMBL29612727 | 0.90 | DDB1 (0.69) | DDB1CRBN | |
| SCHEMBL22609557 | 0.89 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL21071143 | 0.89 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL31577925 | 0.86 | DDB1 (0.51) | DDB1CRBN | |
| SCHEMBL21071349 | 0.85 | DDB1 (0.67) | DDB1CRBN | |
| SCHEMBL22609360 | 0.85 | DDB1 (0.67) | DDB1CRBN | |
| SCHEMBL22609591 | 0.85 | DDB1 (0.61) | DDB1CRBN | |
| SCHEMBL21069275 | 0.85 | DDB1 (0.61) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |