Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18210130 | 1.00 | MAPT (0.38) | MAPTGAATSHRMMP2ANPEP | |
| SCHEMBL21178196 | 1.00 | MAPT (0.38) | MAPTGAATSHRMMP2ANPEP | |
| SCHEMBL21178535 | 1.00 | MAPT (0.38) | MAPTGAATSHRMMP2ANPEP | |
| SCHEMBL376571 | 1.00 | MAPT (0.38) | MAPTGAATSHRMMP2ANPEP | |
| Hydrochloric Acid SCHEMBL18185204 | 0.98 | MAPT (0.36) | MAPTGAATSHRMMP2ANPEP | |
| SCHEMBL21110991 | 0.81 | MMP2 (0.42) | MAPTGAATSHRMMP2ANPEP | |
| SCHEMBL17842674 | 0.81 | MMP2 (0.42) | MAPTGAATSHRMMP2ANPEP | |
| SCHEMBL1923044 | 0.81 | MMP2 (0.42) | MAPTGAATSHRMMP2ANPEP | |
| SCHEMBL743865 | 0.81 | MMP2 (0.42) | MAPTGAATSHRMMP2ANPEP | |
| SCHEMBL10002327 | 0.81 | MMP2 (0.42) | MAPTGAATSHRMMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407754-B2 | Substituted piperidines as kinase inhibitors | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2022-08-09 | — | — | US | disclosed |
| EP-3733674-B1 | AMINO-METHYL PIPERIDINE DERIVATIVE AS KINASE INHIBITOR | DAE WOONG PHARMA (KR) | 2022-06-29 | — | — | EP | disclosed |
| US-20210188854-A1 | Amino-methyl Piperidine Derivative as Kinase Inhibitor | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-06-24 | — | — | US | disclosed |
| EP-3733674-A1 | AMINO-METHYL PIPERIDINE DERIVATIVE AS KINASE INHIBITOR | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-11-04 | — | — | EP | disclosed |
| CN-111527088-A | Amino-methylpiperidine derivatives as kinase inhibitors | 株式会社大熊制药 | 2020-08-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407754-B2 | Substituted piperidines as kinase inhibitors | GRK3, GRK2, GRK4 | MAPT 2168/4885GAA 4470/4885TSHR 1392/4885 |
| US-20210188854-A1 | Amino-methyl Piperidine Derivative as Kinase Inhibitor | MAP3K20, MAP3K1, MAPKAPK5 | MAPT 2837/4885GAA 2570/4885TSHR 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.