SCHEMBL22612156

SCHEMBL22612156

NC(=O)CC(N)C(=O)OF

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DPP9 Q86TI2 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ PMP22 Q01453 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27731700 0.81 — —
SCHEMBL27906557 0.80 ALOX15 (0.36) DPP9ALOX15BLMPMP22KMT2A
SCHEMBL11061010 0.80 ALOX15 (0.36) DPP9ALOX15BLMPMP22KMT2A
SCHEMBL995487 0.80 ALOX15 (0.36) DPP9ALOX15BLMPMP22KMT2A
SCHEMBL6659100 0.78 ALOX15 (0.34) DPP9ALOX15BLMPMP22KMT2A
SCHEMBL1077466 0.78 ALOX15 (0.34) DPP9ALOX15BLMPMP22KMT2A
SCHEMBL17395891 0.78 ALOX15 (0.34) DPP9ALOX15BLMPMP22KMT2A
SCHEMBL27834748 0.77 ALOX15 (0.56) DPP9ALOX15BLMPMP22KMT2A
SCHEMBL23152693 0.76 ALOX15 (0.33) DPP9ALOX15BLMPMP22KMT2A
SCHEMBL7972219 0.76 ALOX15 (0.33) DPP9ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200345851-A1 EPICARDIAL-DERIVED PARACRINE FACTORS FOR REPAIRING CARDIAC TISSUE Sanford Burnham Prebys Medical Discovery Institute 2020-11-05 — — US disclosed
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