SCHEMBL22613554

SCHEMBL22613554

[CH2]CO[C@H]1C[C@H]2C[C@@H]1[C@@H]1CC=C[C@H]21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1660611 1.00 ALDH1A1 (0.33) ALDH1A1POLB
SCHEMBL1661820 0.86 POLB (0.40) ALDH1A1POLB
SCHEMBL10018681 0.80 POLB (0.32) ALDH1A1POLB
SCHEMBL4917975 0.77 ALDH1A1 (0.41) ALDH1A1POLB
SCHEMBL20495536 0.77 ALDH1A1 (0.41) ALDH1A1POLB
SCHEMBL9611064 0.76 ALDH1A1 (0.33) ALDH1A1POLB
SCHEMBL22610194 0.73 TSHR (0.37) ALDH1A1
SCHEMBL3342052 0.73 TSHR (0.37) ALDH1A1
SCHEMBL24635995 0.72
SCHEMBL1819850 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279169-A1 HIGH REFRACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. 2023-09-07 US disclosed
US-11708440-B2 High refractive index, high Abbe compositions Johnson & Johnson Surgical Vision, Inc. (US) 2023-07-25 US disclosed
WO-2020225685-A1 HIGH REFRACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. (US) 2020-11-12 WO disclosed
US-20200347166-A1 HIGH REFRACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. 2020-11-05 US disclosed