Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20970396 | 0.87 | NOS3 (0.33) | HRH3SLC6A4 | |
| SCHEMBL14116874 | 0.77 | HRH3 (0.42) | HRH3SLC6A4NSD2 | |
| SCHEMBL21941251 | 0.76 | MEN1 (0.44) | HRH3 | |
| SCHEMBL20729433 | 0.74 | HRH3 (0.48) | HRH3SLC6A4NSD2 | |
| SCHEMBL12872465 | 0.74 | HRH3 (0.33) | HRH3SLC6A4 | |
| SCHEMBL26581778 | 0.73 | HRH3 (0.46) | HRH3 | |
| SCHEMBL20963278 | 0.73 | HRH3 (0.38) | HRH3SLC6A4NSD2 | |
| SCHEMBL23074854 | 0.72 | GBA1 (0.37) | HRH3SLC6A4 | |
| SCHEMBL9946182 | 0.71 | S1PR1 (0.47) | — | |
| SCHEMBL12685282 | 0.71 | KDM4E (0.42) | HRH3SLC6A4NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10822312-B2 | Substituted quinazoline compounds and methods of use | ARAXES PHARMA LLC (US) | 2020-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10822312-B2 | Substituted quinazoline compounds and methods of use | NRAS, KRAS, HRAS | HRH3 1280/4885SLC6A4 3862/4885NSD2 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.