Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 10/20 | 0.54 |
| ▸ | CA1 | P00915 | 9/20 | 0.54 |
| ▸ | CA2 | P00918 | 9/20 | 0.54 |
| ▸ | CA12 | O43570 | 6/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22618495 | 0.87 | ESR1 (0.52) | USP2L3MBTL1ALBESR1FOLH1 | |
| SCHEMBL22618538 | 0.87 | ESR1 (0.52) | USP2L3MBTL1ALBESR1FOLH1 | |
| SCHEMBL16295184 | 0.86 | FOLH1 (0.68) | USP2L3MBTL1ALBESR1FOLH1 | |
| SCHEMBL24596668 | 0.84 | USP2 (0.57) | USP2L3MBTL1ALBESR1CA9 | |
| Acexamic Acid SCHEMBL30634509 | 0.83 | USP2 (0.55) | USP2L3MBTL1ALBESR1FOLH1 | |
| SCHEMBL22618502 | 0.83 | ALB (0.52) | USP2L3MBTL1ALBESR1FOLH1 | |
| SCHEMBL22618487 | 0.83 | ALB (0.52) | USP2L3MBTL1ALBESR1FOLH1 | |
| SCHEMBL22618551 | 0.83 | ALB (0.52) | USP2L3MBTL1ALBESR1FOLH1 | |
| SCHEMBL22618511 | 0.82 | ALB (0.52) | USP2L3MBTL1ALBESR1FOLH1 | |
| SCHEMBL22618554 | 0.82 | ALB (0.52) | USP2L3MBTL1ALBESR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10822318-B2 | Lactone-based probes and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10822318-B2 | Lactone-based probes and methods of use thereof | MRPL21, QPCTL, ARGLU1 | USP2 4679/4885L3MBTL1 110/4885ALB 2831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.