ARGLU1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to ARGLU1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
L-Arginine Role for Stone Lower Ureter : A Randomized Control Study	PHASE4	COMPLETED
L-arginine Treatment in Mild Hypertension	PHASE4	UNKNOWN
L-Arginine in Pre-Eclampsia	PHASE3	COMPLETED
Effect of L-arginine and Glutamine on Preterm	PHASE2/PHASE3	COMPLETED
Effect of Rosiglitazone on ADMA in Critical Illness	PHASE3	UNKNOWN
The Effect of Arginine on Classic Galactosemia	PHASE2	COMPLETED
Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial	PHASE2	COMPLETED
Intravenous L-Citrulline Influence on the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19	PHASE2	COMPLETED
Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma	PHASE2	COMPLETED
Arginase-1 Peptide Vaccine in Patients With Metastatic Solid Tumors	PHASE1	COMPLETED
The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Hypertensive Versus Healthy Subjects	PHASE1	UNKNOWN
Arginase Inhibition in Ischemia-reperfusion Injury	PHASE1	COMPLETED
The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Healthy Humans. A Dose-response Study	PHASE1	COMPLETED
iNOS With Positron Emission Tomography (PET) in Cellular Inflammation.	EARLY_PHASE1	COMPLETED
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)	nan	RECRUITING
Effect of Arginine and Glutamine on Radiation-induced Oral Mucositis: a Trible Blinded Randomized Controlled Clinical Trial	nan	COMPLETED
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients	nan	COMPLETED
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD	nan	COMPLETED
Preterm Arginine INTake Study	nan	COMPLETED
The Clinical Value of the Nitric Oxide System Components in Asthma and COPD	nan	UNKNOWN
Acute Asthma Responsiveness and B2 Adrenergic Receptors Polymorphisms	nan	COMPLETED
Study of the Articular Microbiota in Rheumatoid Arthritis.	nan	COMPLETED
Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers	nan	COMPLETED
Arginine Synthesis in Healthy Adult Humans	nan	COMPLETED
Effect of L-Citrulline Supplementation on Arginase Activity and Vascular Function in Diabetes	nan	UNKNOWN
Role of Nitric Oxide in Malaria	nan	COMPLETED
Markers of Cardiovascular Risk in Patients With Premature Coronary Artery Disease and Treatment	nan	UNKNOWN
Study of Arginine and Nitric Oxide in Patients With Diabetes	nan	COMPLETED
Detection of EGFR Mutation in Malignant Pleural Effusion of Lung Cancer Patients and Cancer Cell Lines Establishment	nan	UNKNOWN
The Correlation Between Serum PRMT5 Level and Cardiac Ultrasound Indicators in Patients With Heart Failure	nan	ENROLLING_BY_INVITATION

Related proteins — ESM-2 sequence neighbours (a ARGLU1 binder may also engage these)

Protein	Name	Similarity
Q2TA42	—	1.000	Q2TA42 →
Q5ZL35	—	1.000	Q5ZL35 →
Q6P5L7	—	1.000	Q6P5L7 →
Q7ZVW9	—	1.000	Q7ZVW9 →
Q6P2W5	—	1.000	Q6P2W5 →
Q4KLS8	—	1.000	Q4KLS8 →
Q5BJT0	—	0.999	Q5BJT0 →
Q3UL36	—	0.998	Q3UL36 →
P0CB26	—	0.992	P0CB26 →
Q9VL63	—	0.991	Q9VL63 →
B2RY56	—	0.986	B2RY56 →
Q5XHJ5	—	0.986	Q5XHJ5 →
P34433	—	0.985	P34433 →
A2RTL5	—	0.984	A2RTL5 →
Q7ZYR8	—	0.982	Q7ZYR8 →
U2SURP	U2 snRNP-associated SURP motif-containing protein	0.981	landscape →
Q9Z2J4	—	0.981	Q9Z2J4 →
Q32N93	—	0.980	Q32N93 →
Q93712	—	0.979	Q93712 →
Q568K9	—	0.979	Q568K9 →
Q5PQR4	—	0.979	Q5PQR4 →
Q9U213	—	0.978	Q9U213 →
Q0IHP2	—	0.978	Q0IHP2 →
Q95XU6	—	0.978	Q95XU6 →
Q641G3	—	0.977	Q641G3 →
Q4KME6	—	0.977	Q4KME6 →
Q6NWJ4	—	0.977	Q6NWJ4 →
Q9ULR0	—	0.977	Q9ULR0 →
Q7SI59	—	0.976	Q7SI59 →
Q5RDE1	—	0.976	Q5RDE1 →