SCHEMBL22620087

SCHEMBL22620087

CCN(Cc1ccccc1)c1ccc(N(C)c2ccc(N(C)c3ccc(N(CC)Cc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.78
CNR2 P34972 8/20 0.65
CYP2C19 P33261 1/20 0.58
NR1H2 P55055 1/20 0.58
NR1H3 Q13133 1/20 0.58
ALDH1A1 P00352 5/20 0.52
KDM4E B2RXH2 4/20 0.52
MAPT P10636 4/20 0.52
LMNA P02545 3/20 0.52
MAPK1 P28482 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
HPGD P15428 2/20 0.52
KMT2A Q03164 2/20 0.52
MITF O75030 1/20 0.52
RAD52 P43351 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.48
ESRRG P62508 1/20 0.47
CNR1 P21554 3/20 0.47
AOC3 Q16853 1/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179996 0.88 TSHR (1.00) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL17460822 0.86 TSHR (0.81) TSHRCNR2CYP2C19NR1H2NR1H3
Bromide SCHEMBL27967621 0.86 TSHR (0.96) TSHRCNR2CYP2C19NR1H2NR1H3
Hydrochloric Acid SCHEMBL3672654 0.86 TSHR (0.96) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL12763735 0.85 TSHR (0.78) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL11735496 0.85 CYP2C19 (0.81) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL4400874 0.85 TSHR (0.78) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL4407628 0.84 TSHR (0.91) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL5789341 0.83 TSHR (0.75) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL10702263 0.83 TSHR (0.75) TSHRCNR2CYP2C19NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021436-B2 Compound, liquid composition, thermal transfer recording sheet, toner, resist composition for color filter, and color filter CANON KABUSHIKI KAISHA (JP) 2021-06-01 US disclosed
US-20200347007-A1 COMPOUND, LIQUID COMPOSITION, THERMAL TRANSFER RECORDING SHEET, TONER, RESIST COMPOSITION FOR COLOR FILTER, AND COLOR FILTER CANON KABUSHIKI KAISHA (JP) 2020-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200347007-A1 COMPOUND, LIQUID COMPOSITION, THERMAL TRANSFER RECORDING SHEET, TONER, RESIST COMPOSITION FOR COLOR FILTER, AND COLOR FILTER HNRNPR, TECR, TRRAP TSHR 146/4885CNR2 2209/4885CYP2C19 1434/4885
US-11021436-B2 Compound, liquid composition, thermal transfer recording sheet, toner, resist composition for color filter, and color filter HNRNPR, TECR, TRRAP TSHR 146/4885CNR2 2209/4885CYP2C19 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.