Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19353399 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL20892899 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL19353256 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL10264659 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL19353266 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL24244469 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL19943134 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL19353374 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL19353367 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL19353253 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445758-B1 | DIPROVOCIMS: A NEW AND POTENT CLASS OF TLR AGONISTS | SCRIPPS RESEARCH INST (US) | 2020-11-04 | — | — | EP | disclosed |