SCHEMBL22622425

SCHEMBL22622425

CCCCCCCCCCCCCCCCNC(=O)C1CNC[C@H]1C(=O)NCCCCCCCCCCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.61
GNAO1 P09471 1/20 0.61
GNAI1 P63096 1/20 0.61
PRCP P42785 2/20 0.60
NAAA Q02083 1/20 0.57
POLB P06746 1/20 0.57
EPHX1 P07099 7/20 0.53
CASP2 P42575 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22178780 1.00 GNAI3 (0.61) GNAI3GNAO1GNAI1PRCPNAAA
SCHEMBL22179125 1.00 GNAI3 (0.61) GNAI3GNAO1GNAI1PRCPNAAA
SCHEMBL22178794 1.00 GNAI3 (0.61) GNAI3GNAO1GNAI1PRCPNAAA
SCHEMBL22178859 1.00 GNAI3 (0.61) GNAI3GNAO1GNAI1PRCPNAAA
SCHEMBL22178858 1.00 GNAI3 (0.61) GNAI3GNAO1GNAI1PRCPNAAA
SCHEMBL22179123 1.00 GNAI3 (0.61) GNAI3GNAO1GNAI1PRCPNAAA
Hydrochloric Acid SCHEMBL22160532 0.98 GNAI3 (0.64) GNAI3GNAO1GNAI1PRCPNAAA
Hydrochloric Acid SCHEMBL22160701 0.98 GNAI3 (0.64) GNAI3GNAO1GNAI1PRCPNAAA
Hydrochloric Acid SCHEMBL22160504 0.98 GNAI3 (0.64) GNAI3GNAO1GNAI1PRCPNAAA
Hydrochloric Acid SCHEMBL22160621 0.98 GNAI3 (0.64) GNAI3GNAO1GNAI1PRCPNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3445758-B1 DIPROVOCIMS: A NEW AND POTENT CLASS OF TLR AGONISTS SCRIPPS RESEARCH INST (US) 2020-11-04 EP disclosed