Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046706 | 0.81 | CACNA1B (0.55) | CACNA1BCAPN1SCN9ACTSSCTSK | |
| SCHEMBL13833235 | 0.80 | MMP9 (0.51) | CACNA1BALDH1A1MAPTMEN1LMNA | |
| SCHEMBL12226978 | 0.80 | MMP9 (0.51) | CACNA1BALDH1A1MAPTMEN1LMNA | |
| SCHEMBL12393791 | 0.80 | MMP9 (0.51) | CACNA1BALDH1A1MAPTMEN1LMNA | |
| SCHEMBL22695678 | 0.80 | CACNA1B (0.43) | CACNA1BCAPN1ALDH1A1MAPTMEN1 | |
| SCHEMBL18966688 | 0.80 | ANPEP (0.54) | CACNA1BCAPN1LMNASCN9ACTSL | |
| SCHEMBL23446448 | 0.79 | CAPN1 (0.41) | CAPN1ALDH1A1MAPTMEN1LMNA | |
| SCHEMBL22193426 | 0.79 | CACNA1B (0.43) | CACNA1BCAPN1ALDH1A1MAPTMEN1 | |
| SCHEMBL22622527 | 0.79 | CACNA1B (0.43) | CACNA1BALDH1A1MAPTMEN1LMNA | |
| SCHEMBL21949312 | 0.79 | CAPN1 (0.41) | CAPN1ALDH1A1MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964213-B1 | USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES | ALLERGAN INC (US) | 2020-11-04 | — | — | EP | disclosed |