Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.41 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756155 | 0.78 | TAAR1 (0.56) | TAAR1KMT2AALDH1A1IDO1POLB | |
| SCHEMBL20621731 | 0.77 | BRD4 (0.53) | PDGFRBFGFR1KDRKDM4EALDH1A1 | |
| SCHEMBL6753938 | 0.76 | ALDH1A1 (0.60) | TAAR1KMT2AALDH1A1IDO1POLB | |
| SCHEMBL29405275 | 0.74 | ALDH1A1 (0.55) | TAAR1KMT2AALDH1A1IDO1POLB | |
| SCHEMBL2679996 | 0.74 | ALDH1A1 (0.55) | TAAR1KMT2AALDH1A1IDO1POLB | |
| SCHEMBL24820635 | 0.74 | TAAR1 (0.52) | TAAR1KMT2AALDH1A1IDO1POLB | |
| SCHEMBL7098832 | 0.74 | IDO1 (0.57) | TAAR1KMT2AALDH1A1IDO1POLB | |
| SCHEMBL15085764 | 0.74 | TAAR1 (0.55) | TAAR1KMT2AALDH1A1IDO1POLB | |
| SCHEMBL5476505 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10BRD4 | |
| SCHEMBL10696885 | 0.73 | ALDH1A1 (0.54) | TAAR1KMT2AALDH1A1IDO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347045-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347045-A1 | CRBN LIGANDS AND USES THEREOF | CRBN, CRKL, ERBB3 | PDGFRB 866/4885FGFR1 1997/4885KDR 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.