SCHEMBL226246

SCHEMBL226246

Brc1c(SSc2ccc3ccccc3c2Br)ccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.54
▸ ALDH1A1 P00352 5/20 0.48
▸ HSD17B10 Q99714 4/20 0.48
▸ TSHR P16473 3/20 0.48
▸ CYP2A6 P11509 3/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ HPRT1 P00492 1/20 0.44
▸ USP2 O75604 1/20 0.42
▸ PAK1 Q13153 1/20 0.42
▸ HIF1A Q16665 1/20 0.41
▸ CYP1B1 Q16678 1/20 0.41
▸ HPGD P15428 2/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ KEAP1 Q14145 1/20 0.39
▸ PRNP P04156 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ RXFP1 Q9HBX9 1/20 0.39
▸ NCEH1 Q6PIU2 3/20 0.39
▸ CYP1A2 P05177 3/20 0.37
▸ PTPN22 Q9Y2R2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17875623 0.83 POLB (0.50) POLBALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL2203411 0.78 POLB (0.46) POLBALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL1187756 0.73 POLB (0.60) POLBALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL29365294 0.73 ALDH1A1 (0.48) POLBALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL2233625 0.73 PTPN22 (0.58) POLBALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL30187599 0.73 PTPN22 (0.58) POLBALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL3262511 0.73 CYP2A6 (0.58) POLBALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL2231553 0.73 ALDH1A1 (0.48) POLBALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL30550559 0.70 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL253961 0.70 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRCYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 — — US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 — — US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 — — US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 — — US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 — — US claimed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 — — US claimed
US-10933285-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2021-03-02 — — US disclosed
US-20200197757-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-06-25 — — US disclosed
US-10596419-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2020-03-24 — — US disclosed
US-20200086174-A1 A GOLF BALL COMPRISING A VERY-LOW MELT FLOW INNER COVER LAYER COMPOSITION JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2020-03-19 — — US disclosed
US-20200047033-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-02-13 — — US disclosed
US-10478675-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2019-11-19 — — US disclosed
US-10478674-B2 Golf ball comprising a very-low melt flow inner cover layer composition ACUSHNET COMPANY (US) 2019-11-19 — — US disclosed
US-6417278-B1 POLYBUTADIENE CORE; INTERMEDIATE RESILIENT POLYMER AND REINFORCING POLYBUTYLENE; INORGANIC SULFIDE, ORGANIC SULFIDE, AND OR GROUP VI COMPOUND CATALYST ACUSHNET COMPANY 2002-07-09 — — US disclosed
US-20020016224-A1 Filler-impregnated golf ball core blend ACUSHNET COMPANY 2002-02-07 — — US disclosed
US-20020016219-A1 INSERT ON THE STRIKE SURFACE OF THE CLUB FORMED FROM THE CONVERSION REACTION OF POLYBUTADIENE, A FREE RADICAL SOURCE, AND A CIS-TO-TRANS CATALYST FORM A POLYBUTADIENE REACTION PRODUCT WITH INCREASED TRANS CONTENT ACUSHNET COMPANY 2002-02-07 — — US disclosed
US-20020013184-A1 Golf ball with multi-layer cover ACUSHNET COMPANY 2002-01-31 — — US disclosed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 — — US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 — — US disclosed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 — — US disclosed
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