Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22624921 | 0.94 | MAOB (0.34) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL22624942 | 0.92 | MAOB (0.35) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL25854728 | 0.92 | MAOB (0.38) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL22625121 | 0.92 | KDM4E (0.37) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL22624920 | 0.91 | MAOB (0.37) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL25849217 | 0.89 | MAOB (0.39) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL22625303 | 0.86 | THRB (0.39) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL22625007 | 0.86 | MAOB (0.37) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL22625239 | 0.86 | MAOB (0.36) | MAOBMAOASLC10A1NPC1RAB9A | |
| SCHEMBL22625243 | 0.85 | MAOB (0.37) | MAOBMAOASLC10A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583102-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |