Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ALPI | P09923 | 2/20 | 0.58 |
| ▸ | TYR | P14679 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226048 | 0.81 | NPC1 (0.63) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL5695416 | 0.81 | TYR (0.74) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL19462942 | 0.81 | MAPT (0.61) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL5695444 | 0.81 | TYR (0.74) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10848923 | 0.80 | MAPT (0.65) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL6674966 | 0.78 | POLB (0.55) | MAPTMEN1KMT2AHPGDALPI | |
| SCHEMBL10853946 | 0.78 | MAPT (0.89) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10853940 | 0.78 | MAPT (0.89) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL29226032 | 0.77 | MAPT (0.76) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL5695453 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223439-A1 | AURONES AND METHODS OF USING AURONES TO TREAT TUBERCULOSIS | Middle Tennessee State University (US) | 2020-11-05 | — | — | WO | disclosed |