Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.40 |
| ▸ | PIK3R2 | O00459 | 9/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.40 |
| ▸ | PIK3R5 | Q8WYR1 | 9/20 | 0.40 |
| ▸ | PIK3R3 | Q92569 | 9/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16339759 | 0.93 | PIK3CD (0.37) | UGCGPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL16377961 | 0.82 | CYP11B1 (0.37) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16377819 | 0.81 | PIK3CD (0.37) | UGCGPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17783265 | 0.81 | CYP19A1 (0.36) | CYP3A4CYP19A1CYP11B1CYP11B2IRAK4 | |
| SCHEMBL16339761 | 0.80 | CYP19A1 (0.32) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16340232 | 0.80 | UGCG (0.38) | UGCGPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL24519352 | 0.80 | PIK3CD (0.36) | UGCGPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL20580158 | 0.80 | PIK3CD (0.37) | UGCGPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL20579991 | 0.77 | UGCG (0.34) | UGCGPIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL16377696 | 0.77 | UGCG (0.34) | UGCGPIK3CDPIK3R2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |