Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 15/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.36 |
| ▸ | PIK3R5 | Q8WYR1 | 15/20 | 0.36 |
| ▸ | PIK3R3 | Q92569 | 15/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16378004 | 0.90 | UGCG (0.33) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16377782 | 0.90 | CCNA2 (0.33) | — | |
| SCHEMBL16377819 | 0.90 | PIK3CD (0.37) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29670696 | 0.88 | CCNA2 (0.36) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16339733 | 0.88 | CCNA2 (0.36) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL19326993 | 0.87 | MAPT (0.34) | — | |
| SCHEMBL16377947 | 0.85 | UGCG (0.33) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16377831 | 0.85 | PIK3CD (0.45) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16377822 | 0.84 | PIK3CD (0.34) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16377985 | 0.84 | PIK3CD (0.34) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365199-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | MERCK PATENT GMBH (DE) | 2022-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365199-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | FSHR, GNRHR, LHCGR | PIK3CD 927/4885PIK3R2 274/4885PIK3CA 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.