SCHEMBL226266

SCHEMBL226266

CCc1ccccc1COC(=O)c1ccccc1C(=O)OCc1ccccc1CC

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.62
ALDH1A1 P00352 8/20 0.58
L3MBTL1 Q9Y468 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
CYP3A4 P08684 3/20 0.53
MAPK1 P28482 2/20 0.53
TP53 P04637 1/20 0.53
LMNA P02545 2/20 0.51
KDM4E B2RXH2 1/20 0.51
CASP3 P42574 2/20 0.49
SENP8 Q96LD8 2/20 0.49
SENP7 Q9BQF6 2/20 0.49
SENP6 Q9GZR1 2/20 0.49
HSD17B10 Q99714 1/20 0.49
NPC1 O15118 2/20 0.47
HTT P42858 1/20 0.47
GLA P06280 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671689 0.91 TSHR (0.50) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL5155639 0.87 ALDH1A1 (0.58) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL28084232 0.85 ALDH1A1 (0.73) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL82573 0.84 TSHR (0.60) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL227321 0.82 TSHR (0.59) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL1456598 0.82 ALDH1A1 (0.62) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL223433 0.82 ALDH1A1 (0.62) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL227558 0.82 ALDH1A1 (0.62) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL225446 0.82 ALDH1A1 (0.62) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL223458 0.82 ALDH1A1 (0.62) TSHRALDH1A1L3MBTL1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2647668-B1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME ADEKA CORP (JP) 2019-08-14 EP disclosed
EP-3075784-B1 PROCESS FOR PRODUCING MASTERBATCH ADEKA CORP (JP) 2018-10-03 EP disclosed
US-9890256-B2 Process for producing masterbatch ADEKA CORPORATION (JP) 2018-02-13 US disclosed
EP-2796487-B1 METHOD FOR PRODUCING MASTERBATCHES ADEKA CORP (JP) 2017-08-02 EP disclosed
EP-2407514-B1 REINFORCED POLYESTER RESIN COMPOSITION ADEKA CORP (JP) 2017-03-01 EP disclosed
US-9527966-B2 Method for producing masterbatches ADEKA CORPORATION (JP) 2016-12-27 US disclosed
US-20160347917-A1 PROCESS FOR PRODUCING MASTERBATCH ADEKA CORPORATION (JP) 2016-12-01 US disclosed
EP-3075784-A1 PROCESS FOR PRODUCING MASTERBATCH Adeka Corporation (JP) 2016-10-05 EP disclosed
US-20140350139-A1 METHOD FOR PRODUCING MASTERBATCHES ADEKA CORPORATION (JP) 2014-11-27 US disclosed
EP-2796487-A1 METHOD FOR PRODUCING MASTERBATCHES Adeka Corporation (JP) 2014-10-29 EP disclosed
US-8829084-B2 Reinforced polyester resin composition ADEKA CORPORATION (JP) 2014-09-09 US disclosed
EP-2647668-A1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME Adeka Corporation (JP) 2013-10-09 EP disclosed
US-20130253145-A1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME ADEKA CORPORATION (JP) 2013-09-26 US disclosed
EP-2407514-A1 REINFORCED POLYESTER RESIN COMPOSITION Adeka Corporation (JP) 2012-01-18 EP disclosed
US-20120004363-A1 REINFORCED POLYESTER RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-01-05 US disclosed