Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16339733 | 0.93 | CCNA2 (0.36) | CCNA2CDK2CCNA1TGFBR1ACVR1 | |
| SCHEMBL29670696 | 0.93 | CCNA2 (0.36) | CCNA2CDK2CCNA1TGFBR1ACVR1 | |
| SCHEMBL19326993 | 0.92 | MAPT (0.34) | CCNA2CDK2CCNA1TGFBR1ACVR1 | |
| SCHEMBL24519352 | 0.90 | PIK3CD (0.36) | — | |
| SCHEMBL16377828 | 0.88 | CCNA2 (0.32) | CCNA2CDK2CCNA1TGFBR1ACVR1 | |
| SCHEMBL17789664 | 0.88 | NR1H4 (0.32) | — | |
| SCHEMBL24519344 | 0.88 | JMJD6 (0.41) | — | |
| SCHEMBL16377995 | 0.88 | CACNA2D1 (0.30) | — | |
| SCHEMBL22607652 | 0.87 | ROCK2 (0.32) | CCNA2CDK2CCNA1MAPT | |
| SCHEMBL16377787 | 0.87 | MAPT (0.31) | CCNA2CDK2CCNA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| WO-2014209980-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |