Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | KDM1A | O60341 | 6/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548978 | 1.00 | ACHE (0.36) | ACHEKDM1AKDM1BCYP11B1CYP11B2 | |
| SCHEMBL8253437 | 1.00 | ACHE (0.36) | ACHEKDM1AKDM1BCYP11B1CYP11B2 | |
| SCHEMBL8613089 | 1.00 | ACHE (0.36) | ACHEKDM1AKDM1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL29020128 | 0.98 | ACHE (0.39) | ACHEKDM1AKDM1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL29961672 | 0.98 | ACHE (0.39) | ACHEKDM1AKDM1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8612954 | 0.98 | ACHE (0.39) | ACHEKDM1AKDM1BCYP11B1CYP11B2 | |
| SCHEMBL15109677 | 0.88 | ACHE (0.40) | ACHEKDM1AKDM1BCYP11B1CYP11B2 | |
| SCHEMBL8183412 | 0.84 | ACHE (0.36) | ACHEKDM1AKDM1BCYP11B1CYP11B2 | |
| SCHEMBL31730446 | 0.84 | KDM1A (0.49) | ACHEKDM1AKDM1BKCNH2 | |
| SCHEMBL803167 | 0.80 | ACHE (0.40) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3964518-B1 | CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2026-01-28 | — | — | EP | disclosed |
| US-12157755-B2 | CD73 inhibitor, preparation method therefor and application thereof | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2024-12-03 | — | — | US | disclosed |
| EP-4272836-A2 | CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| EP-4272836-A2 | CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| US-20220162253-A1 | CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
| US-20220162253-A1 | CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
| EP-3964518-A1 | CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2022-03-09 | — | — | EP | disclosed |
| WO-2020221209-A1 | CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2020-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12157755-B2 | CD73 inhibitor, preparation method therefor and application thereof | ENTPD5, ENTPD1, NT5E | ACHE 97/4885KDM1A 729/4885KDM1B 796/4885 |
| US-20220162253-A1 | CD73 INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ENTPD5, ENTPD1, NT5E | ACHE 97/4885KDM1A 729/4885KDM1B 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.