Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22630075 | 0.92 | NR1H4 (0.32) | — | |
| SCHEMBL22629954 | 0.86 | SOAT2 (0.34) | — | |
| SCHEMBL22630072 | 0.85 | — | — | |
| SCHEMBL22630037 | 0.84 | HDAC1 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL21735440 | 0.82 | HDAC1 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL21735437 | 0.82 | HDAC1 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL22630077 | 0.80 | — | — | |
| SCHEMBL22628877 | 0.79 | HDAC6 (0.32) | HDAC6 | |
| SCHEMBL22630078 | 0.78 | F9 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL22628929 | 0.76 | NR1H4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |