Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22629018 | 0.90 | KDM1A (0.44) | EPHX2HSD11B1KDM1ACCR5CHRM2 | |
| SCHEMBL22628949 | 0.85 | EPHX2 (0.43) | EPHX2HSD11B1KDM1ACCR5CHRM2 | |
| SCHEMBL2307422 | 0.84 | — | — | |
| SCHEMBL2584008 | 0.83 | EPHX2 (0.42) | EPHX2HSD11B1CCR5CHRM2SMYD3 | |
| SCHEMBL2584012 | 0.83 | EPHX2 (0.42) | EPHX2HSD11B1CCR5CHRM2SMYD3 | |
| SCHEMBL22629906 | 0.81 | EPHX2 (0.41) | EPHX2HSD11B1CCR5CHRM2SMYD3 | |
| SCHEMBL2585948 | 0.81 | CCR5 (0.43) | EPHX2HSD11B1CCR5CHRM2SMYD3 | |
| SCHEMBL2585944 | 0.81 | CCR5 (0.43) | EPHX2HSD11B1CCR5CHRM2SMYD3 | |
| SCHEMBL22629613 | 0.80 | SMYD3 (0.49) | EPHX2HSD11B1CCR5SMYD3 | |
| SCHEMBL5007422 | 0.80 | EPHX2 (0.43) | EPHX2HSD11B1CCR5CHRM2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200345700-A1 | LSD1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200345700-A1 | LSD1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | KDM1B, KDM1A, KDM2A | EPHX2 1598/4885HSD11B1 340/4885KDM1A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.