Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 8/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 8/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22347897 | 0.87 | HSD11B1 (0.43) | KDM1AHSD11B1NR1H4CHRM2SLC6A2 | |
| SCHEMBL22629019 | 0.85 | HSD11B1 (0.35) | KDM1AHSD11B1NR1H4CHRM2FABP4 | |
| SCHEMBL22347720 | 0.84 | NR1H4 (0.42) | KDM1AHSD11B1NR1H4CHRM2FABP4 | |
| SCHEMBL22628919 | 0.79 | HSD11B1 (0.47) | HSD11B1NR1H4CHRM2SLC6A2SLC6A4 | |
| SCHEMBL22347606 | 0.75 | HSD11B1 (0.44) | HSD11B1NR1H4CHRM2ADORA2AADORA1 | |
| SCHEMBL22348493 | 0.75 | HSD11B1 (0.44) | HSD11B1NR1H4CHRM2ADORA2AADORA1 | |
| SCHEMBL12251752 | 0.74 | HSD11B1 (0.50) | KDM1AHSD11B1NR1H4CHRM2CHRM4 | |
| SCHEMBL22347953 | 0.73 | HSD11B1 (0.43) | HSD11B1NR1H4CHRM2SLC6A2SLC6A4 | |
| SCHEMBL22629097 | 0.73 | HSD11B1 (0.44) | HSD11B1NR1H4CHRM2SLC6A2SLC6A4 | |
| SCHEMBL22629751 | 0.73 | KDM1A (0.56) | KDM1ANR1H4DGAT1SOAT1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200345700-A1 | LSD1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200345700-A1 | LSD1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | KDM1B, KDM1A, KDM2A | KDM1A 2/4885HSD11B1 340/4885NR1H4 2006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.