SCHEMBL22629693

SCHEMBL22629693

Cc1cccc(C(=O)Nc2cccc(C(C)C)c2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 14/20 0.74
KCNK9 Q9NPC2 10/20 0.74
KCNH2 Q12809 1/20 0.74
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
RXFP1 Q9HBX9 1/20 0.69
POLB P06746 1/20 0.68
NPC1 O15118 2/20 0.63
RAB9A P51151 2/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
TP53 P04637 1/20 0.60
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
GAA P10253 1/20 0.59
MAPT P10636 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
NT5E P21589 1/20 0.58
CSF1R P07333 1/20 0.58
RET P07949 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23844177 0.91 FADS1 (0.62) KCNK3KCNK9KCNH2MEN1KMT2A
SCHEMBL21377636 0.90 KCNK3 (0.72) KCNK3KCNK9KCNH2MEN1KMT2A
SCHEMBL21377682 0.90 KCNK3 (0.72) KCNK3KCNK9KCNH2MEN1KMT2A
SCHEMBL12218052 0.87 NPC1 (0.72) KCNK3KCNK9KCNH2MEN1KMT2A
SCHEMBL5262986 0.87 NPC1 (0.60) KCNK3KCNK9KCNH2MEN1KMT2A
SCHEMBL8283426 0.86 KCNK9 (0.69) KCNK3KCNK9MEN1KMT2APOLB
SCHEMBL9978845 0.86 FADS1 (0.64) KCNK3KCNK9KCNH2MEN1KMT2A
SCHEMBL4253897 0.86 KCNK3 (0.93) KCNK3KCNK9KCNH2MEN1KMT2A
SCHEMBL15238437 0.84 SMN1; SMN2 (0.77) KCNK3KCNK9KCNH2MEN1KMT2A
SCHEMBL15238606 0.83 SMN1; SMN2 (0.56) KCNK3KCNK9KCNH2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200369901-A1 DISPERSION, INK JET RECORDING METHOD, RECORDED MATERIAL, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-11-26 US disclosed
US-20200347252-A1 INK COMPOSITION FOR INK JET PRINTING, IMAGE FORMING METHOD, AND RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2020-11-05 US disclosed