Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.51 |
| ▸ | ITGB6 | P18564 | 17/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.51 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21745032 | 1.00 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL2232143 | 0.89 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL2232146 | 0.89 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL13237151 | 0.89 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL21745024 | 0.88 | ITGAV (0.53) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL2231847 | 0.87 | ITGAV (0.49) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL2231825 | 0.87 | ITGAV (0.49) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL2231837 | 0.87 | ITGAV (0.49) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL13237165 | 0.85 | ITGB3 (0.47) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL328144 | 0.85 | ITGAV (0.52) | ITGAVITGB6ITGB3ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613739-B1 | INTEGRIN ANTAGONISTS | Oxurion NV (BE) | 2020-11-04 | — | — | EP | disclosed |